Antiproliferative effects of Ceratonia siliqua L. on mouse hepatocellular carcinoma cell line

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Antiproliferative effects of Ceratonia siliqua L. on mouse hepatocellular carcinoma cell line.

Extracts from pods and leaves of carob (Ceratonia siliqua L.) were tested for their ability to inhibit cell proliferation of mouse hepatocellular carcinoma cell line (T1). The two extracts showed a marked alteration of T1 cell proliferation in a dose-related fashion reaching the maximal effect at 1 mg/ml. Moreover, we demonstrated that leaf and pod extracts were able to induce apoptosis in T1 c...

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ABSTRACT          Background and Objectives: Capparis spinosa has been used in traditional medicine for various applications including treatment of liver disorders and cancer. We studied the effects of this plant on cell proliferation and morphological characteristics of PLC/PRF/5 liver cancer cell line.         Method...

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Clonal Propagation of Carob (ceratonia Siliqua L., Fabaceae)

Mature seeds of carob tree (Ceratonia siliqua L.) were germinated on hormone free MS medium. Efforts were made to develop multiple shoots by using axillary buds of in vitro grown seedlings on MS medium fortified with different concentrations of BA singly and BA in combination with IAA or GA3. Axillary buds produced single shoot with a moderate amount of callus at the base of the explant after c...

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Effects of Various Treatments on Seed Germination and Growth of Carob (ceratonia Siliqua L.)

In this study, Ceratonia siliqua L. carob seeds harvested from both wild and cultivated genotypes in Turkey were subjected to mechanical scarification, soaking in hot water and dipping in sulfuric acid. All treatments hastened seed germination and seedling growth of carob compared to control. The germination percentage of control seeds were similar for both wild and cultivated genotypes (13%) a...

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ژورنال

عنوان ژورنال: Fitoterapia

سال: 2002

ISSN: 0367-326X

DOI: 10.1016/s0367-326x(02)00227-7